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	Provedor de dados BABT (1) Genet. Mol. Biol. (1) Autor Zhang,Zhengdong (2) Gao,Lin (1) Jing,Fengxuan (1) Li,Chunying (1) Li,Hong (1) Li,Kai (1) Liu,Jiangtao (1) Liu,Ling (1) Liu,Yufeng (1) Shen,Zhu (1) Xie,Xiaoyao (1) Xing,Hiu (1) Zhou,Wenwei (1) Mais... Palavra-chave COMT (1) Classification numbering (1) Enzyme (1) Gene polymorphism (1) Genetic susceptibility (1) Metabolic network alignment (1) Psoriasis (1) Sequence similarity (1) Similarity measure (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2016 (1) 2009 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Comparisons Between Different Methods in Measuring Enzyme Similarity for Metabolic Network Alignment BABT Zhou,Wenwei; Liu,Jiangtao; Xing,Hiu; Zhang,Zhengdong; Xie,Xiaoyao; Jing,Fengxuan. Metabolic network alignments enable comparison of the similarities and differences between pathways in two metabolic networks and help to uncover the conserved sub-blocks therein. Such analysis is important in the understanding of metabolic networks and species evolution. The fundamental parts of metabolic network alignment algorithms all involve comparisons of the similarity between two enzymes as a similarity measure of network nodes. As a result, the study of methods for measuring enzyme similarity becomes highly relevant. Currently, two approaches are mainly used to measure enzyme similarity. One of the methods is based on similarity measures of gene or protein sequences; the other is based on enzyme classification. In this study, multiple metabolic... Tipo: Info:eu-repo/semantics/article Palavras-chave: Metabolic network alignment; Enzyme; Similarity measure; Classification numbering; Sequence similarity. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100405 Polymorphism of the catechol-O-methyltransferase gene in Han Chinese patients with psoriasis vulgaris Genet. Mol. Biol. Gao,Lin; Gao,Lin; Li,Hong; Li,Hong; Li,Kai; Li,Kai; Shen,Zhu; Liu,Ling; Li,Chunying; Zhang,Zhengdong; Liu,Yufeng. Psoriasis vulgaris is defined by a series of linked cellular changes in the skin: hyperplasia of epidermal keratinocytes, vascular hyperplasia and ectasia, and infiltration of T lymphocytes, neutrophils and other types of leukocytes in the affected skin. Catechol-O-methyltransferase ( COMT ) 158 polymorphism can reduce the activity of the COMT enzyme that may trigger defective differentiation of keratinocytes in psoriasis. Immunocytes can degrade and inactivate catecholamines via monamine oxidase (MAO) and COMT in the cells. We hypothesized that the COMT-158 G > A polymorphism was associated with the risk of psoriasis vulgaris in Han Chinese people. In a hospital-based case-control study, 524 patients with psoriasis vulgaris and 549... Tipo: Info:eu-repo/semantics/article Palavras-chave: COMT; Gene polymorphism; Genetic susceptibility; Psoriasis. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572009000100005 Registros recuperados: 2 Primeira ... 1 ... Última

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